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Surgery
Which of the following is true regarding intravenous administration of chemotherapy?
Subcutaneous extravasation of carmustine (BCNU) or 5-fluorouracil (5-FU) usually causes ulceration
Extravasation of doxorubicin rarely causes serious ulceration because the agent binds quickly to tissue nucleic acid
Serious and progressive ulceration can be expected following extravasation of vincristine or vinblastine
Problems of wound healing should be anticipated if systemic 5-FU therapy is begun less than 2 week postoperatively
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