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Biochemistry
SCD is caused by a recessive, single-nucleotide mutation in the beta globin gene of Hgb. All of the following are TRUE about Sickle cell disease, EXCEPT:
Single nucleotide change results in change of Glutamine to Valine
Sticky patch is generated as a result of replacement of a non polar residue with a polar residue
HbS confers resistance against malaria in heterozygotes
RFLP results from a single base change
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