**Core Concept**
Naloxone is an opioid antagonist used to reverse opioid overdose by competitively binding to opioid receptors. During resuscitation, it is crucial to consider the mother's opioid use and potential for neonatal abstinence syndrome (NAS) in the child.
**Why the Correct Answer is Right**
Naloxone administration can precipitate NAS in a neonate whose mother is physically dependent on opioids. This is because naloxone can rapidly reverse the maternal opioid blockade, exposing the fetal opioid receptors to high levels of opioids. This can lead to severe withdrawal symptoms in the neonate, including seizures, respiratory distress, and even death.
**Why Each Wrong Option is Incorrect**
**Option A:** Methadone maintenance therapy is a common treatment for opioid use disorder. Naloxone is not contraindicated in this scenario.
**Option B:** Benzodiazepines are not typically used as a primary treatment for opioid use disorder. Naloxone is still the preferred choice for reversing opioid overdose in this scenario.
**Option C:** Fentanyl is an opioid analgesic commonly used in anesthesia. Naloxone is still used to reverse fentanyl overdose, but caution should be exercised due to the risk of NAS in neonates.
**Clinical Pearl / High-Yield Fact**
In neonates, maternal opioid use can lead to NAS, which can be prevented by administering naloxone to the mother rather than the neonate. However, this is not a standard practice due to the risk of maternal respiratory depression.
**Correct Answer:** D. Methadone.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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