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177133 Pharmacology

An old man enters the hospital with myocardial infarction and a severe ventricular arrhythmia. The antiarrhythmic drug chosen has a narrow therapeutic window. The minimum toxic plasma concentration is 1.5 times the minimum therapeutic plasma concentration. The half life is 6 hrs. It is essential to maintain the plasma concentration above the minimum therapeutic level to prevent a possible lethal arrhythmia. Of the following, the most appropriate dosing regimen would be

AOnce a day
BTwice a day
CFour times a day
DConstant intravenous infusion
Pharmacology
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