Unknown

A 70-year-old male patient presented with forgetfulness of keys, or doing household chores. The patient has difficulty in driving and takes more time in recognising face of family members. On examination, MMSE was 20/30. Consciousness was intact, no focal neurological deficit was present. The following finding was seen on Bielschowsky stain. Which of the following anatomical regions depict the earliest change in this disease?