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Surgery
Hypothermia (0deg to 4deg C) is a critical component of successful organ cold storage because:
Oxygen is more soluble in cold solutions and provides a continual supply for energy metabolism
There is no way to suppress microbial growth except by cooling and slowing the growth rate
Hypothermia diminishes energy requirements and allows the limited energy reserve to keep the organ alive
It slows metabolism and the enzymic processes that would destroy the cell
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