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Pharmacology
Fibrates -- false is
They increase lipoprotein lipase activity through PPAR alpha, and cause increased lipolysis of triglycerides.
They are better absorbed when taken on empty stomach, than when taken with food
Cause utricaria, rashes, alopecia, myopathy and G.I. distress.
Are first line of drugs in severe dysbetalipoproteinemias and hyperiglyceridemias.
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