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Pharmacology
A patient diagnosed as having ventilator associated pneumonia, is on treatment with ceftriaxone and amikacin. Culture and sensitivity turned out to be positive for ESBL producing Klebsiella infection. The most appropriate next action should be:
Continue same antibiotic but at higher dose
Replace ceftazidime for ceftriaxone
Remove amikacin and add quinolone
Change over to imipenem
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