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Pathology
A 15-year-old boy with Albright hereditary osteodystrophy (AHO) is rushed to emergency room with severe muscle cramps and convulsions. The child has a history of mental retardation. Laboratory studies reveal hypocalcemia and elevated blood levels of PTH. Which of the following distinguishes this patient's endocrinopathy from hypoparathyroidism seen in DiGeorge syndrome?
Abnormalities in cardiac conduction and contractility
Accelerated degradation of PTH
Decreased neuromuscular excitability
End-organ unresponsiveness to PTH
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