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Pathology
A 28-year-old man complains of nasal obstruction, bloody nose, cough, and bloody sputum. A chest X-ray displays cavitated lesions and multiple nodules within both lung fields. Urinalysis reveals 3+ hematuria and red blood cell casts. Laboratory studies show anemia and elevated serum levels of C-ANCA (antineutrophil cytoplasmic antibody). Peripheral eosinophils are not increased. A renal biopsy exhibits focal glomerular necrosis with crescents and vasculitis affecting arterioles and venules. Which of the following best describes the renal disease of the patient?
Chronic nephritic syndrome
Nephrotic syndrome
Rapidly progressive glomerulonephritis
Type I membranoproliferative glomerulonephritis
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