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Pathology
A 13-year-old male presents with bilateral enlargement of his breasts. Physical exam is otherwise unremarkable, and the breast enlargement is thought to be a normal variation at pubey. Histologic sections of breast tissue would most likely reveal
Proliferation of ducts in hyalinized fibrous tissue with periductal edema
Atrophic ductal structures with increased numbers of lipocytes
Dilated ducts filled with granular, necrotic, acidophilic debris
Granulomatous inflammation surrounding ducts with numerous plasma cells
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