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Pathology
A tall man with gynecomastia and testicular atrophy has a testicular biopsy that shows sparse, completely hyalinized seminiferous tubules with a complete absence of germ cells and only rare Seoli cells. Leydig cells are present in large clumps between the hyalinized tubules. Which of the following genetic disorders should be suspected?
Testicular feminization syndrome
Trisomy 18
Trisomy 21
47, XXY
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