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Pathology
A 37-year-old primigravida at 30 weeks' gestation has noted increasing pedal edema, headaches, confusion, and decreased urine output for the past 2 weeks. She now exhibits seizure activity and then lapses into a coma. On physical examination, her temperature is 36.8degC, pulse is 82/min, respirations are 24/min, and blood pressure is 145/95 mm Hg. Her heart rate is regular, and lung fields are clear. The abdomen is soft, and bowel sounds are present. There is pitting edema to the thighs. No vaginal bleeding is noted, and the cervix is not effaced. Laboratory findings show hemoglobin, 11.9 g/dL; hematocrit, 35.8%; platelet count, 63,500/ mm3; WBC count, 8180/ mm3; glucose, 151 mg/dL; total protein, 6.1 g/dL; albumin, 3.2 g/dL; total bilirubin, 2.3 mg/dL; AST, 88 U/L; ALT, 103 U/L; alkaline phosphatase, 253 U/L; and prothrombin time, 32 seconds (INR 2.8). Urinalysis shows specific gravity of 1.024, pH 6, 4+ proteinuria, 1+ glucosuria, and no blood. An ultrasound examination shows a viable 30-week fetus. What condition is most likely present in this patient?
Abruptio placentae
Budd-Chiari syndrome
Dilated cardiomyopathy
HELLP syndrome
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