Pathology

A 60-year-old mildly obese woman is admitted to the hospital with a chief complaint of recurrent chest pain on exertion. The patient reports several episodes of chest pain over the past several years and painful leg cramps when walking. Fasting blood glucose (160 mg/dL) and total serum cholesterol (370 mg/dL) are high. The ECG is normal and blood tests for cardiac-specific proteins are negative. Chest pain in this patient is most likely due to which of the following underlying conditions?