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Medicine
A seven year old child with recurrent chest infections and exocrine pancreatic insufficiency is suspected of having cystic fibrosis. Sweat chloride levels have been observed to be between 40-60 mmol/l on two separate occasions. Which of the following test should be performed next to suppo the diagnosis of Cystic fibrosis?
Repeat sweat chloride levels on a different day
Demonstrate an abnormal 72 hour fecal fat collection
Demonstrate an abnormal nasal potential difference
Demonstrate an abnormal F508 mutation by DNA analysis
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