8 times the ULN; ALT > 5 times the ULN Nonalcoholic fatty liver disease: AST and ALT > 4 times the ULN Acute viral hepatitis or toxin-related hepatitis with jaundice: AST and ALT > 25 times the ULN Ischemic hepatopathy (ischemic hepatitis, shock liver): AST and ALT > 50 times the ULN (in addition the lactate dehydrogenase is often markedly elevated) Chronic hepatitis C virus infection: Wide variability, typically normal to less than twice the ULN, rarely more than 10 times the ULN Chronic hepatitis B virus infection: Levels fluctuate; the AST and ALT may be normal, though most patients have mild to moderate elevations (approximately twice the ULN); with exacerbations, levels are more than 10 times the ULN Acid maltase deficiency (AMD) is an autosomal recessive disease characterized by an excessive accumulation of glycogen within lysosome-derived vacuoles in nearly all types of cells.">