A known case of Crohn's disease presented with worsening fatigue over the last 2 months. The 50 year old lady was on Infliximab for the past 2 years and did not have many relapses. Lab findings revealed, Hemoglobin - 8 gm/dl Low serum iron Low serum ferritin Increased TIBC Low transferrin saturation The peripheral blood smear and the hemoglobin electrophoresis is given below. Which of the following is the most likely cause of the above condition: -