Surgery Which of the following is true regarding intravenous administration of chemotherapy? A Subcutaneous extravasation of carmustine (BCNU) or 5-fluorouracil (5-FU) usually causes ulceration B Extravasation of doxorubicin rarely causes serious ulceration because the agent binds quickly to tissue nucleic acid C Serious and progressive ulceration can be expected following extravasation of vincristine or vinblastine D Problems of wound healing should be anticipated if systemic 5-FU therapy is begun less than 2 week postoperatively 💡 Explanation Which of the following is true regarding intravenous administration of chemotherapy? ✓ Correct Answer: D. Problems of wound healing should be anticipated if systemic 5-FU therapy is begun less than 2 week postoperatively