**Core Concept**
The question pertains to screening tests for cardiovascular disease, specifically focusing on identifying the most economical and effective method. The underlying principle involves the use of risk factor assessment, clinical examination, and basic laboratory tests to identify individuals at high risk of developing cardiovascular disease.

**Why the Correct Answer is Right**
The correct answer involves the use of the **Framingham Risk Score (FRS)**, a widely used tool for assessing cardiovascular risk. The FRS takes into account various risk factors such as age, sex, total cholesterol, HDL cholesterol, smoking status, and systolic blood pressure to estimate the 10-year risk of developing cardiovascular disease. This approach is considered economical and effective as it is based on easily obtainable data and does not require expensive or invasive tests.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is likely referring to a more extensive and expensive screening test such as a coronary angiogram, which is not necessary for initial risk assessment.
* **Option B:** This option might suggest using a single risk factor such as high blood pressure or high cholesterol as a screening tool, which is not sufficient to accurately predict cardiovascular risk.
* **Option C:** This option is likely incorrect as it is not a recognized screening tool for cardiovascular disease.

**Clinical Pearl / High-Yield Fact**
A key aspect of the Framingham Risk Score is that it takes into account the concept of "net benefit," which means that the benefits of treating a patient with a given risk score must outweigh the potential risks and costs of treatment.

**Correct Answer:** A. The Framingham Risk Score is the most economical and best screening tool for identifying individuals at high risk of developing cardiovascular disease.