Which of the following structures are not involved in development of diaphragm?
**Core Concept**
The diaphragm is a dome-shaped muscle that separates the chest cavity from the abdominal cavity, playing a crucial role in respiration. Its development involves the fusion of several embryological structures, including the pleuroperitoneal membranes, the septum transversum, and the body wall.
**Why the Correct Answer is Right**
The diaphragm develops from the septum transversum, the pleuroperitoneal membranes, and the body wall. The septum transversum forms the central tendon of the diaphragm, while the pleuroperitoneal membranes contribute to the formation of the peripheral part of the diaphragm. The body wall contributes to the muscular part of the diaphragm.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is likely referring to the **phrenic nerves**, which are indeed involved in the innervation of the diaphragm, but not in its development. The phrenic nerves arise from the cervical spinal cord and provide motor innervation to the diaphragm.
**Option B:** This option might be referring to the **pleura**, which are indeed closely associated with the diaphragm, as they line the pleural cavities that contain the lungs. However, the pleura are not directly involved in the development of the diaphragm.
**Option C:** This option is likely referring to the **pericardium**, which surrounds the heart and is not directly involved in the development of the diaphragm. The pericardium forms separately from the diaphragm.
**Option D:** This option is likely referring to the **thymus**, which is a gland involved in the immune system and is located in the anterior superior mediastinum. The thymus is not directly involved in the development of the diaphragm.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that the development of the diaphragm is closely associated with the development of the pleural cavities and the lungs. However, the diaphragm itself develops from separate embryological structures, and its development is not directly linked to the development of other thoracic organs like the heart or the thymus.
**Correct Answer: B. Pleura**