A patient of schizophrenia was staed on haloperidol 5 mg. Next day, he presented with uprolling of eyes. Complete neurological examination revealed no spasticity or any other abnormality. Visual acuity and ophthalmoscopic findings are normal. Most likely diagnosis is :

**Core Concept**
Haloperidol, a typical antipsychotic, can cause extrapyramidal side effects (EPS) due to its blockade of dopamine D2 receptors in the nigrostriatal pathway, leading to motor disturbances.

**Why the Correct Answer is Right**
The patient's presentation with uprolling of the eyes, also known as oculogyric crisis, is a type of dystonia associated with EPS. This condition is thought to result from the blockade of dopamine D2 receptors in the basal ganglia, particularly in the oculomotor nuclei. Haloperidol's high potency and rapid onset contribute to the development of this side effect. The normal neurological examination, visual acuity, and ophthalmoscopic findings suggest that the patient does not have a more serious neurological condition.

**Why Each Wrong Option is Incorrect**
**Option A:**
This option is likely incorrect because it does not specify a condition related to the patient's presentation of oculogyric crisis.

**Option B:**
This option is likely incorrect because it does not describe a condition associated with EPS or haloperidol use.

**Option C:**
This option is likely incorrect because it does not specify a condition related to the patient's presentation of oculogyric crisis.

**Clinical Pearl / High-Yield Fact**
EPS, including dystonias, are more common with high-potency antipsychotics like haloperidol and can be managed with anticholinergic medications.

**Correct Answer:**
C. Oculogyric crisis

✓ Correct Answer: B. Acute dystonia