**Core Concept**
The question tests the student's knowledge of the sensory receptors responsible for detecting vibration and pressure stimuli in the skin. Paccinian corpuscles are specialized mechanoreceptors that respond to changes in pressure and vibration, playing a crucial role in sensing tactile and vibratory stimuli.

**Why the Correct Answer is Right**
Paccinian corpuscles, also known as lamellated corpuscles, contain a spiral-shaped structure that allows them to detect changes in pressure and vibration. When a stimulus is applied, the fluid-filled canals within the corpuscle are deformed, triggering a mechanical signal that is transmitted to the sensory nerve fibers. This signal is then interpreted by the brain as a vibration or pressure sensation. Paccinian corpuscles are located in the dermal layer of the skin and are particularly abundant in areas such as the fingertips and palms.

**Why Each Wrong Option is Incorrect**
**Option A:** Merkel's discs are type I mechanoreceptors that respond to sustained pressure and are responsible for detecting texture and shape. They do not respond to vibration or changes in pressure.
**Option B:** Ruffini's end organs are type II mechanoreceptors that respond to sustained pressure and are involved in detecting stretching and skin stretch. They do not play a role in vibration sensation.
**Option D:** Meissner's corpuscles are type II mechanoreceptors that respond to light touch and are involved in detecting texture and shape. They are not responsible for detecting vibration or changes in pressure.

**Clinical Pearl / High-Yield Fact**
Paccinian corpuscles are responsible for the sensation of vibration and pressure, which is essential for tasks such as playing musical instruments or typing on a keyboard. Damage to these receptors can result in impaired tactile and vibratory sensation, making everyday activities more difficult.

**✓ Correct Answer: C. Paccinian corpuscle**