**Core Concept**
Amiodarone is a complex medication known for its antiarrhythmic properties, but it also comes with a range of potential side effects due to its iodine content and lipophilic nature. These side effects can affect various organs and systems in the body, including the lungs, liver, thyroid, and eyes.

**Why the Correct Answer is Right**
Amiodarone-induced pulmonary toxicity is a well-documented phenomenon, characterized by symptoms such as dyspnea, cough, and chest tightness. However, a productive cough is not typically associated with amiodarone-induced pulmonary toxicity. Instead, patients often present with non-productive cough or shortness of breath. The correct answer is D. Productive cough because amiodarone-induced pulmonary toxicity typically presents with a non-productive cough.

**Option A:** Pulmonary fibrosis is a known complication of amiodarone therapy, characterized by the scarring of lung tissue. This can lead to symptoms such as shortness of breath and cough.

**Option B:** Corneal micro-deposits are a common side effect of amiodarone therapy, resulting from the deposition of amiodarone in the cornea. These deposits can cause visual disturbances and are often reversible.

**Option C:** Amiodarone-induced hepatotoxicity can range from mild elevations in liver enzymes to severe liver damage, including cirrhosis. Patients may present with symptoms such as fatigue, jaundice, and abdominal pain.

**Clinical Pearl / High-Yield Fact**
Amiodarone-induced pulmonary toxicity can be a life-threatening complication of therapy. Clinicians should closely monitor patients on amiodarone for signs of pulmonary toxicity, including non-productive cough, shortness of breath, and chest tightness.

**Correct Answer:**
✓ Correct Answer: D. Productive cough