The thresholds for permanent sterility in women for prepubeal exposure and premenopausal exposure conditions are
Correct Answer: 12 Gy and 2 Gy, respectively
Description: In women, radiation is highly effective at inducing permanent ovarian failure, but there is a marked age dependence insensitivity. The dose required to induce permanent sterility varies from 12 Gy (1,200 rad) prepubeal to 2 Gy (200 rad) premenopausal. Pronounced hormonal changes, comparable to those associated with the natural menopause, accompany radiation-induced sterilization in females.Reference: Eric J Hall Textbook of Radiobiology for Radiologist; 5th edition
Category:
Radiology
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