**Core Concept**
The management of postoperative pain in infants requires careful consideration of their unique physiology and the potential risks of analgesic medications. Infants have a developing liver and kidneys, which affect their ability to metabolize and eliminate drugs. Additionally, the American Academy of Pediatrics recommends the use of non-pharmacological methods of pain relief, such as sucrose or breast milk, in conjunction with pharmacological interventions.

**Why the Correct Answer is Right**
The use of acetaminophen (paracetamol) is recommended for postoperative pain relief in infants due to its favorable pharmacokinetic profile and safety profile. Acetaminophen is metabolized in the liver and excreted in the urine, making it a suitable choice for infants. However, it should be used in conjunction with non-pharmacological methods of pain relief, such as sucrose or breast milk, to minimize the risk of adverse effects.

**Why Each Wrong Option is Incorrect**
**Option A:** Opioids, such as morphine, are not recommended for routine postoperative pain relief in infants due to their potential for respiratory depression and other adverse effects.
**Option B:** Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are not typically used for postoperative pain relief in infants due to their potential for gastrointestinal and renal toxicity.
**Option C:** Local anesthetics, such as lidocaine, are not typically used for postoperative pain relief in infants due to their potential for toxicity and the need for precise dosing.

**Clinical Pearl / High-Yield Fact**
The American Academy of Pediatrics recommends the use of non-pharmacological methods of pain relief, such as sucrose or breast milk, in conjunction with pharmacological interventions to minimize the risk of adverse effects in infants.

**Correct Answer:** C.