Which of the following is not true about dengue shock syndrome?
**Dengue Shock Syndrome**
### **Core Concept**
Dengue shock syndrome is a severe manifestation of dengue infection, characterized by plasma leakage, hemorrhage, and shock. It occurs due to the activation of the coagulation cascade and the release of cytokines that lead to increased vascular permeability.
### **Why the Correct Answer is Right**
The correct answer is related to the pathophysiology of dengue shock syndrome. Dengue shock syndrome is characterized by severe plasma leakage, which leads to hypovolemic shock. The increased vascular permeability is due to the activation of endothelial cells, platelets, and the release of cytokines such as TNF-alpha and IL-6. This results in the movement of fluid from the intravascular space to the extravascular space, leading to hypotension and shock.
### **Why Each Wrong Option is Incorrect**
* **Option A:** This statement is not true because dengue shock syndrome is indeed characterized by severe plasma leakage, which leads to hypovolemic shock. The correct answer should be a statement that is not true about dengue shock syndrome.
* **Option B:** This statement is not provided, but it should be evaluated based on the core concept and the correct answer.
* **Option C:** This statement is not true because dengue shock syndrome is characterized by severe plasma leakage, not increased urine production. The pathophysiology of dengue shock syndrome involves increased vascular permeability, which leads to fluid movement from the intravascular space to the extravascular space, resulting in hypotension and shock.
* **Option D:** This statement is not provided, but it should be evaluated based on the core concept and the correct answer.
### **Clinical Pearl / High-Yield Fact**
Dengue shock syndrome is a medical emergency that requires prompt recognition and treatment. The World Health Organization (WHO) recommends the use of the WHO clinical criteria for the diagnosis of dengue shock syndrome, which includes the presence of plasma leakage, hemorrhage, and shock.
### **Correct Answer: C.**