**Core Concept**
The restoration of the epidermis over an abraded area is a complex process involving the coordinated effort of various cell types, growth factors, and extracellular matrix components. This process is essential for the maintenance of skin integrity and function.
**Why the Correct Answer is Right**
The correct answer is **B. Epidermal cell migration and proliferation**. The process of wound healing is initiated by the migration of keratinocytes from the surrounding skin into the wound area. These cells then proliferate and differentiate to form a new epidermis. This process is facilitated by the production of growth factors, such as platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF), which promote cell migration and proliferation. The newly formed epidermis is then anchored to the underlying dermis through the production of extracellular matrix components, such as collagen and elastin.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it refers to the process of angiogenesis, which is the formation of new blood vessels from pre-existing ones. While angiogenesis is an important aspect of wound healing, it is not directly responsible for the restoration of the epidermis.
**Option C:** This option is incorrect because it refers to the process of inflammation, which is the body's initial response to injury. While inflammation is a necessary step in the wound healing process, it is not directly responsible for the restoration of the epidermis.
**Clinical Pearl / High-Yield Fact**
It's worth noting that the process of wound healing is a complex, multi-stage process that involves the coordinated effort of various cell types, growth factors, and extracellular matrix components. Understanding the mechanisms of wound healing is essential for the development of effective treatments for skin injuries and diseases.
**Correct Answer: B. Epidermal cell migration and proliferation**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.