**Core Concept**
Pre-exposure prophylaxis for rabies involves administering a combination of vaccines to prevent the disease after exposure to the virus. The World Health Organization (WHO) recommends a specific regimen for pre-exposure prophylaxis, which includes multiple doses of rabies vaccine administered over a period of time.

**Why the Correct Answer is Right**
The WHO recommends that pre-exposure prophylaxis for rabies consists of two doses of rabies vaccine administered on days 0 and 7. This regimen provides adequate immunity against the rabies virus and is essential for individuals who work with animals or are at high risk of exposure. The rabies vaccine stimulates the production of antibodies against the rabies virus, which helps to prevent the virus from replicating and causing the disease.

**Why Each Wrong Option is Incorrect**
* **Option A:** Administering a single dose of rabies vaccine is not sufficient for pre-exposure prophylaxis, as it may not provide adequate immunity against the rabies virus.
* **Option B:** The recommended interval between doses of rabies vaccine for pre-exposure prophylaxis is 7 days, not 14 days.
* **Option C:** The recommended number of doses for pre-exposure prophylaxis is 2, not 3.

**Clinical Pearl / High-Yield Fact**
It's essential to note that post-exposure prophylaxis for rabies involves a different regimen, which includes immediate washing of the wound, administration of rabies immunoglobulin, and a series of rabies vaccine doses over 14-21 days.

**Correct Answer:** C. 2 doses of rabies vaccine administered on days 0 and 7.