The process increasing the ability for phagocytosis of foreign bodies by body is called –
**Core Concept**
The process of enhancing phagocytosis is a key mechanism of the immune system, involving the ingestion and destruction of foreign particles and microorganisms by phagocytic cells. This process is crucial for defending against infections and maintaining tissue homeostasis.
**Why the Correct Answer is Right**
The correct answer refers to the phenomenon of opsonization, where the surface of foreign particles is marked with molecules that facilitate their recognition and engulfment by phagocytic cells. This process involves the deposition of opsonins, such as immunoglobulin G (IgG) and complement component 3b (C3b), which bind to the surface of pathogens and make them more susceptible to phagocytosis. The Fc receptors on the surface of phagocytic cells, such as neutrophils and macrophages, then recognize the bound opsonins and trigger the engulfment of the pathogen.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it does not describe a process that increases phagocytosis. Instead, it might refer to a process that inhibits or reduces phagocytic activity.
* **Option B:** This option is incorrect because it is a term that refers to the killing of cells, not the enhancement of phagocytosis. Apoptosis is a process of programmed cell death that is distinct from phagocytosis.
* **Option C:** This option is incorrect because it does not accurately describe a process that increases phagocytosis. Instead, it might refer to a process that inhibits or reduces phagocytic activity.
**Clinical Pearl / High-Yield Fact**
Opsonization is a critical process for enhancing phagocytosis, and defects in this process can lead to impaired immune function and increased susceptibility to infections. For example, individuals with chronic granulomatous disease (CGD) have impaired phagocytic function due to defects in NADPH oxidase, leading to recurrent infections.
**Correct Answer: D. Opsonization**