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46869 Medicine

A 75 year old man with no past medical history presents with increasing shortness of breath over 6 months. He previously worked at a shipyard where he had significant exposure to asbestos. He has a large right-sided pleural effusion. Pleural aspiration is performed and reveals an exudate but cytopathological examination identifies no malignant cells. CT scanning reveals circumferential pleural thickening but no other abnormalities. Which test is most likely to give a diagnosis?

AThoracoscopy
BBronchoscopy
CEchocardiogram
DRepeat pleural aspiration
Medicine
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46870 Dental

A concerned mother brings her 7-day-old son to his pediatrician after he develops a rash. Examination reveals a cluster of erythematous vesicles localized to the child’s mouth. The child’s vital signs are all within normal limits, and aside from the rash and mild irritability he appears healthy. A sample of tissue is taken from the base of a ruptured vesicle and subjected to the Tzanck test . The child is treated with the most commonly prescribed agent for this condition. Which of the following is a serious adverse effect associated with this drug?

AAgranulocytosis
BFulminant liver failure
COsteopenia
DRenal toxicity
Dental
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