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40979 Anatomy

Regarding termination of drug action

ADrugs must be excreted from the body to terminate their action
BMetabolism of drugs always abolishes their Pharmalogical activity
CHepatic metabolism and renal excretion are the two most impoant mechanism involved
DDistribution of a drug out of bloodstream terminated drugs effect
Anatomy
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40983 Pharmacology

Fibrates – false is

AThey increase lipoprotein lipase activity through PPAR alpha, and cause increased lipolysis of triglycerides.
BThey are better absorbed when taken on empty stomach, than when taken with food
CCause utricaria, rashes, alopecia, myopathy and G.I. distress.
DAre first lines of drugs in severe dysbetalipoproteinemias and hypertriglyceridemias.
Pharmacology
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