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38899 Medicine

A 30 year old presented with a skin lesion in his right axilla. A presumptive diagnosis of staphylococcal skin carbuncle is made & patient is treated with empiric trimethoprim/ sulfamethoxazole. After 2 days, the patient came to emergency with excessive weakness, abdominal pain & dark coloured urine. O/E- vitals are normal & jaundice is present. Lab studies show a drop in Hb from 14 g/dl to 8 g/dl & rise in bilirubin levels. Urine dipstick is positive for bilirubin. Peripheral blood smear is shown below. What could be the possible diagnosis of the patient?

AGlucose 6-phosphate dehydrogenase (G6PD) deficiency
BHemolytic-uremic syndrome
CHereditary spherocytosis
DIron deficiency anaemia
Medicine
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38904 Pathology

A 5 year old male child presents with continuous bleeding from mouth. He had h/o fall early in the morning while playing. No h/o bruising or hematoma. He is taking amoxycillin for his middle ear infection. O/E he is stable and there is a small laceration in the lower lip with oozing of blood. Hb 12.8g%, hematocrit 35.4%, WBC count 8400/mm3, Platelets 300 X 109/L- Prothrombin time 11.5 seconds, aPTT 37.2 seconds. Diagnosis

AHemophilia A
BVon Willebrand disease
CGlanzmann thrombasthenia
DBernard Soulier syndrome
Pathology
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