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163058 Pathology

A 17-year-old boy comes to the physician because of edema of both legs as well as pen- orbital edema There is no history of diarrhea and no urinary symptoms suggestive of infection. He had a throat infection 3 weeks ago. His blood pressure is 110/70 mmHg. He undergoes a kidney biopsy and light microscopy is normal. The patient is treated and makes a full recovery. Which of the following is the most likely diagnosis?

AAccelerated hypertension
BANCA associated vasculitis
CMinimal change glomerulonephnitis
DPost-streptococcal glomerulonephritis
Pathology
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163062 Medicine

A 55 year old male, who is a known case of severe persistent asthma since 14 years of age presents with acute exacerbation of asthma. The disease was well controlled upto 54 years with high dose inhaled corticosteroids. For the past 12 months the disease was not in good control. He complains of nocturnal cough, limitation of daily activities in spite of good compliance with medications. Spirometry was suggestive of bronchial asthma with partial irreversibility of airway obstruction. What is the cause for poor disease control?

AAirway epithelial shedding
BAirway inflammation
CAirway remodeling
DAirway hyperresponsiveness
Medicine
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