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162560 Radiology

A 38 years old female patient presented with gradually worsening unsteady gait as well as numbness and tingling in hands and feet. At the time of admission neurological examination revealed slight weakness of distal muscles, bilaterally absent ankle jerk reflexes, bilaterally extensor plantar reflexes, and loss of position and vibration senses in all extremities. Brain MRI was unremarkable. T2 weighted MRI of the cervical spinal cord showed high signal lesions in the posterior columns extending to the upper thoracic spinal cord . This finding is caused due to deficiency of?

AVitamin B-1
BVitamin B-12
CVitamin C
DVitamin A
Radiology
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162565 Pathology

A 6-year-old girl presents with a 2-week history of a skin rash over her buttocks and legs and joint pain. The parents report seeing blood in the urine. Physical examination reveals palpable purpuric skin lesions and markedly swollen knees. The results of laboratory studies reveal abnormally high erythrocyte sedimentation rate (30 mm/h), BUN of 25 mg/dL, and serum creatinine of 3 mg/dL. Urinalysis demonstrates RBCs and RBC casts. The stool guaiac test is positive. Biopsy of lesional skin reveals deposits of IgA in the walls of small blood vessels. Which of the following is the most likely diagnosis?

AHenoch-Schonlein purpura
BHypersensitivity vasculitis
CKawasaki disease
DPolyarteritis nodosa
Pathology
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