Most common viruses isolated from herpangina are:
**Core Concept**
Herpangina is a clinical syndrome characterized by the sudden onset of small, painful vesicles or ulcers in the posterior one-third of the mouth, particularly on the tonsils and soft palate. It is primarily caused by viral infections.
**Why the Correct Answer is Right**
The most common viruses isolated from herpangina cases are Coxsackie A viruses, specifically Coxsackie A viruses 2, 4, 5, 6, 10, and 16. These viruses belong to the Enterovirus genus and are highly contagious. They cause herpangina by infecting the mucosal cells of the oral cavity, leading to inflammation and vesicle formation.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because Coxsackie B viruses are more commonly associated with aseptic meningitis and hand-foot-and-mouth disease, rather than herpangina.
* **Option B:** This option is incorrect because Herpes simplex virus is more commonly associated with oral herpes, characterized by the presence of painful vesicles on the lips, rather than herpangina.
* **Option C:** This option is incorrect because Adenovirus is more commonly associated with pharyngoconjunctival fever and acute hemorrhagic cystitis, rather than herpangina.
**Clinical Pearl / High-Yield Fact**
It's essential to note that herpangina is typically a self-limiting condition, and treatment is mainly focused on symptom management, such as pain relief and hydration. However, if left untreated, herpangina can lead to dehydration and secondary bacterial infections.
**Correct Answer: C. Coxsackie A viruses.**