Okay, let's tackle this question. The scenario is a child with meningoencephalitis, chorioretinitis, and intracranial calcifications. The question is asking for the most likely diagnosis.

First, I need to recall the TORCH infections, which are a group of pathogens that can cause congenital infections. TORCH stands for Toxoplasma, Other (like syphilis, varicella), Rubella, Cytomegalovirus (CMV), and Herpes. These infections can lead to various congenital abnormalities.

The symptoms mentioned here are meningoencephalitis (inflammation of the brain and meninges), chorioretinitis (inflammation of the choroid and retina), and intracranial calcifications. Let's break them down. Meningoencephalitis could be due to several viruses, but when combined with other signs, it points to a specific pathogen. Chorioretinitis is a key sign here. Intracranial calcifications are also a red flag for congenital infections.

CMV is a common cause of congenital infections and can present with microcephaly, hepatosplenomegaly, jaundice, and intracranial calcifications. Chorioretinitis is also a known manifestation in congenital CMV. Toxoplasmosis can cause chorioretinitis but is less commonly associated with intracranial calcifications. Rubella can cause congenital defects like cataracts and cardiac issues but not typically chorioretinitis. Herpes can cause encephalitis but not the triad mentioned here. Toxoplasmosis might present with hydrocephalus and calcifications but the chorioretinitis is a key point here.

So, the most likely diagnosis is congenital CMV. The clinical triad of meningoencephalitis, chorioretinitis, and intracranial calcifications is classic for CMV. The other options don't fit all three symptoms as well. The correct answer should be Cytomegalovirus (CMV).

**Core Concept**
Congenital infections, particularly **Cytomegalovirus (CMV)**, are a leading cause of **meningoencephalitis**, **chorioretinitis**, and **intracranial calcifications** in neonates. These triad findings are hallmark features of **congenital CMV infection**, which is the most common intrauterine viral infection in developed countries.

**Why the Correct Answer is Right**
Congenital CMV causes **inflammation of the central nervous system (meningoencephalitis)** due to direct viral cytopathic effects. **Chorioretinitis** results from retinal damage by the virus, often leading to visual impairment. **Intracranial calcifications** arise from periventricular gliosis and necrosis caused by viral replication in the developing brain. CMV is the most likely diagnosis because it uniquely combines these three findings more than other TORCH agents.

**Why Each Wrong Option is Incorrect**
**Option A:** *Toxoplasmosis* causes chorioretinitis and calcifications but lacks the encephalitis component in most cases.
**Option B:** *Rubella* causes catar

✓ Correct Answer: B. Toxoplasmosis