**Core Concept**
Rat bites are a potential source of zoonotic infections, including leptospirosis, rat-bite fever, and rabies. Effective management of rat bites involves a combination of wound care, antibiotic prophylaxis, and post-exposure prophylaxis against rabies.

**Why the Correct Answer is Right**
Rat-bite fever is caused by *Streptobacillus moniliformis* or *Spirillum minus*, and leptospirosis is caused by *Leptospira* species. Tetanus toxoid is administered to prevent tetanus infection, which can occur through contaminated wounds. Washing the wound with soap and using antiseptic cream are essential for wound care and preventing secondary infections. However, rabies immunoglobulin is not typically required for post-exposure prophylaxis after a rat bite, as the risk of rabies transmission is low. The Centers for Disease Control and Prevention (CDC) recommend post-exposure prophylaxis with rabies vaccine alone.

**Why Each Wrong Option is Incorrect**
**Option A:** Vaccinate with antirabies vaccine - This is not typically required for rat bites, as the risk of rabies transmission is low.
**Option B:** Give tetanus toxoid - While tetanus toxoid is recommended for tetanus prophylaxis, the primary concern with rat bites is bacterial infection, not tetanus.
**Option A:** Rarely need rabies immunoglobulin - This is correct, as the risk of rabies transmission is low after a rat bite.

**Clinical Pearl / High-Yield Fact**
When managing animal bites, it's essential to consider the animal's vaccination status, the bite's severity, and the patient's risk factors for zoonotic infections.

**✓ Correct Answer: C. cde. Wash with soap, Use antiseptic cream, Rarely need rabies immunoglobulin.**