Pediatrics If the first child is heterozygous and the wife is homozygous for an autosomal-recessive gene, what will be the outcome? A 75% children affected B No child affected, but all are carriers C 50% children affected, rest are carriers D 25% children affected, rest are carriers 💡 Explanation If the first child is heterozygous and the wife is homozygous for an autosomal-recessive gene, what will be the outcome? ✓ Correct Answer: C. 50% children affected, rest are carriers