“Id” reaction is seen in
**Core Concept**
The "id" reaction refers to an immunological phenomenon where an antigen combines with an antibody to form an immune complex, which then precipitates out of the blood and accumulates in various tissues, leading to inflammation and tissue damage. This reaction is a type of hypersensitivity reaction, specifically a type III hypersensitivity reaction.
**Why the Correct Answer is Right**
The "id" reaction is seen in conditions such as serum sickness, systemic lupus erythematosus (SLE), and rheumatoid arthritis. In these conditions, the immune complexes formed by the antigen-antibody reaction deposit in the blood vessels and tissues, leading to inflammation and tissue damage. The complement system is activated, and various cytokines are released, contributing to the inflammatory response.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the Arthus reaction is a different type of hypersensitivity reaction, characterized by localized inflammation and immune complex deposition in the skin.
**Option B:** This option is incorrect because the tuberculin reaction is a type of delayed hypersensitivity reaction, also known as a cell-mediated immune response, which is different from the "id" reaction.
**Option C:** This option is incorrect because the Farber reaction is not a recognized immunological phenomenon.
**Clinical Pearl / High-Yield Fact**
The "id" reaction is an example of a type III hypersensitivity reaction, which can lead to significant tissue damage and inflammation if left untreated. It is essential to recognize the clinical manifestations of this reaction to provide appropriate treatment and prevent long-term complications.
**Correct Answer: D. Serum sickness.**