HDN is seen due to deficiency of vitamin
Correct Answer: K
Description: Vit k is necessary for coagulation. Factors dependent on Vit k are synthesised on the liver as inactive zymogen. They undergo gamma carboxylation, which requires Vit k as a cofactor. Clinical Manifestations of Deficiency i. Hemorrhagic disease of the newborn is attributed to vitamin K deficiency. The newborns, especially premature infants have relative vitamin K deficiency. This is due to lack of hepatic stores, limited oral intake (breast milk has very low levels, 15 mg/litre) and absence of intestinal bacterial flora. ii. It is often advised that pre-term infants be given prophylactic doses of vitamin K (1 mg Menadione iii. In children and adults, Vitamin K deficiency may be manifested as bruising tendency, ecchymotic patches, mucous membrane haemorrhage, post-traumatic bleeding Ref: DM Vasudevan - Textbook of Biochemistry, 8th edition, page no: 462
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now