Feature (s) of dyskeratosis is/are all except : (PGI June 2007)
**Core Concept**
Dyskeratosis is a histopathological feature characterized by the premature keratinization of cells, particularly in the epidermis. This process leads to the formation of dyskeratotic cells, which are enlarged and have an abnormal, hyperchromatic nucleus.
**Why the Correct Answer is Right**
Dyskeratosis is a feature of several conditions, including dyskeratosis congenita, a rare genetic disorder. It is also seen in other dermatological conditions like psoriasis and lichen planus. The process of dyskeratosis involves the abnormal expression of keratin proteins, leading to the disruption of the normal keratinization process.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because dyskeratosis is not a feature of benign conditions like keratosis pilaris, which is a harmless skin condition characterized by small, rough bumps on the skin.
**Option B:** This option is incorrect because dyskeratosis is not a feature of seborrheic keratoses, which are benign skin growths that are often found on sun-exposed areas of the body.
**Option C:** This option is incorrect because dyskeratosis is not a feature of eczema, which is a chronic inflammatory skin condition characterized by dry, itchy, and scaly skin.
**Clinical Pearl / High-Yield Fact**
Dyskeratosis is an important feature to recognize in histopathology, as it can be a clue to the diagnosis of various dermatological conditions.
**Correct Answer: B. Seborrheic keratoses are benign skin growths that are often found on sun-exposed areas of the body.