**Core Concept**
Salter-Harris fractures are a classification of physeal (growth plate) injuries that occur in children and adolescents. These fractures are characterized by their involvement of the growth plate, metaphysis, and epiphysis, leading to disruption of the normal growth pattern.

**Why the Correct Answer is Right**
Salter-Harris type IV fractures occur through a combination of the growth plate, metaphysis, and epiphysis. This type of fracture is caused by a shearing force that displaces the epiphysis from the metaphysis, resulting in a fracture through the growth plate and the surrounding bone. The fracture line in a Salter-Harris type IV fracture typically extends through the growth plate, the metaphysis, and the epiphysis, leading to a characteristic "corner" or "corner fragment" appearance on radiographs. The involvement of the growth plate and surrounding bone in this type of fracture can lead to growth disturbances and deformities if not properly treated.

**Why Each Wrong Option is Incorrect**
**Option A:** Fracture occur through growth plate only - This is incorrect because Salter-Harris type IV fractures involve not only the growth plate but also the metaphysis and epiphysis.

**Option B:** Fracture occur through growth plate & metaphysis only - This is incorrect because Salter-Harris type IV fractures also involve the epiphysis.

**Option D:** Fracture occur through epiphysis only - This is incorrect because Salter-Harris type IV fractures involve the growth plate, metaphysis, and epiphysis, not just the epiphysis alone.

**Clinical Pearl / High-Yield Fact**
It is essential for orthopaedic surgeons and emergency physicians to accurately diagnose and treat Salter-Harris fractures, as improper management can lead to growth disturbances, deformities, and long-term functional deficits. A thorough understanding of the classification and characteristics of these fractures is crucial for optimal patient outcomes.

**✓ Correct Answer:** C. Fracture occur through growth plate, metaphysic & epiphysis