True about Rabies a) Bats Transmit disease in some parts of the world b) Brainstem encephalitis is characteristic c) Negri bodies commonly found in thalamus and anterior pituitary d) Paraesthesia is not seen e) Recovery is the usual course

**Core Concept**
Rabies is a viral zoonotic disease caused by a lyssavirus, primarily transmitted through the bite of an infected mammal. The virus targets the central nervous system (CNS) and is characterized by its severe and often fatal outcome.

**Why the Correct Answer is Right**
The correct answer involves two key aspects of rabies: its transmission and characteristic CNS pathology. Bats are indeed a natural reservoir of rabies virus in some parts of the world, making option **a)** correct. Brainstem encephalitis is a characteristic feature of rabies, resulting from the viral infection of neurons in the CNS, thus making option **b)** correct. This leads to a range of clinical manifestations, including increased salivation, hydrophobia, and paralysis of the face and limbs.

**Why Each Wrong Option is Incorrect**
**Option C:** Negri bodies, which are pathognomonic for rabies, are typically found in the neurons of the hippocampus, cerebellum, and Purkinje cells, but not commonly in the thalamus and anterior pituitary. This makes option **c)** incorrect.
**Option D:** Paraesthesia, or abnormal sensations such as tingling or numbness, is often seen in patients with rabies, particularly in the face and extremities. This makes option **d)** incorrect.
**Option E:** Recovery from rabies is extremely rare, and the disease is almost always fatal once symptoms appear. This makes option **e)** incorrect.

**Clinical Pearl / High-Yield Fact**
It is essential for clinicians to be aware of the classic symptoms of rabies, including hydrophobia, aerophobia, and paralysis of the face and limbs. Early recognition and prompt post-exposure prophylaxis (PEP) are critical in preventing the development of the disease.

**✓ Correct Answer: A. ab**