Drug of choice for infantile spasm is –
Correct Answer: Vigabatrin
Description: Myoclonic epilepsy may be
Infantile spasm or Infantile myoclonus or West syndrome
Juvenile myoclonic epilepsy
Infantile spasm (Infantile mvoclonus or west syndrome)
The onset is usually between 3-8 months of life
It is characterized by a triad of -
i) Salaam spells (sudden dropping of the head & flexion of arms)
ii) Mental retardation
iii) Hypsarrhythmic pattern of EEG (diffuse high voltage slow spike and chaotic activity)
The spasm occurs in clusters usually on waking.
Prognosis for normal mental development is poor.
Treatment of infantile myoclonus
ACTH and corticosteroids are given for 2-12 weeks, depending upon response.
Vigabatrin is the DOC Now.
Category:
Pediatrics
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