**Core Concept**
Disulfiram-like reaction refers to a condition where a patient experiences symptoms similar to those seen with disulfiram (an alcohol deterrent medication), such as flushing, nausea, and vomiting, but without the ingestion of disulfiram. This reaction occurs due to the inhibition of aldehyde dehydrogenase, an enzyme responsible for metabolizing acetaldehyde, a toxic byproduct of alcohol metabolism.

**Why the Correct Answer is Right**
Certain medications can induce a disulfiram-like reaction by inhibiting aldehyde dehydrogenase, leading to an accumulation of acetaldehyde. This is seen with medications like metronidazole, which is an antibiotic used to treat various bacterial infections. Metronidazole inhibits aldehyde dehydrogenase, causing an accumulation of acetaldehyde and resulting in a disulfiram-like reaction.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it is not a known cause of disulfiram-like reaction.
**Option B:** This option is incorrect as it does not inhibit aldehyde dehydrogenase.
**Option C:** This option is incorrect as it is not commonly associated with disulfiram-like reaction.

**Clinical Pearl / High-Yield Fact**
When prescribing medications like metronidazole, it is essential to advise patients to avoid consuming alcohol, as this can exacerbate the disulfiram-like reaction and lead to severe symptoms.

**Correct Answer: C. Metronidazole.**