**Core Concept**
CYP 450 enzymes are a family of cytochrome P450 enzymes that play a crucial role in the metabolism of various drugs. Induction of these enzymes leads to an increase in their expression and activity, resulting in enhanced metabolism of the affected drugs.

**Why the Correct Answer is Right**
CYP 450 inducers are substances that increase the expression and activity of CYP enzymes, leading to increased metabolism of the affected drugs. This can result in decreased plasma concentrations of the drugs and reduced therapeutic effects. Examples of CYP 450 inducers include rifampicin, phenobarbital, and carbamazepine, which increase the expression of CYP3A4, a major CYP enzyme responsible for the metabolism of many drugs.

* **Option A:** is incorrect because it is not a known CYP 450 inducer.
* **Option B:** is incorrect because it is actually a CYP 450 inhibitor, which decreases the activity of CYP enzymes.

**Clinical Pearl / High-Yield Fact**
When starting or stopping a CYP 450 inducer, it is essential to monitor the plasma concentrations of affected drugs and adjust their dosages accordingly to avoid subtherapeutic or toxic effects.

**Correct Answer:** C. Carbamazepine, rifampicin, and phenobarbital are well-known CYP 450 inducers.