Congenital toxoplasmosis – False is aEUR’
**Core Concept**
Congenital toxoplasmosis occurs when the Toxoplasma gondii parasite is transmitted from the mother to the fetus during pregnancy, leading to infection in the developing fetus. This can result in a range of complications, including neurological and ocular abnormalities.
**Why the Correct Answer is Right**
The correct answer is related to the pathogenesis of congenital toxoplasmosis. Toxoplasma gondii infects the fetus by crossing the placenta, where it invades and replicates within the fetal tissues. This invasion is facilitated by the parasite's ability to evade the host's immune response. The parasite also manipulates the host's cellular environment to create an environment conducive to its own replication.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not accurately describe the pathogenesis of congenital toxoplasmosis.
**Option B:** This option is incorrect because it misrepresents the mechanism of Toxoplasma gondii infection in the fetus.
**Option C:** This option is incorrect because it does not provide a clear understanding of the parasite's ability to infect the fetus.
**Option D:** This option is incorrect because it does not accurately describe the consequences of congenital toxoplasmosis.
**Clinical Pearl / High-Yield Fact**
Toxoplasma gondii infection during pregnancy is a significant risk factor for congenital toxoplasmosis. Pregnant women should avoid undercooked meat, especially pork and lamb, and wash their hands thoroughly after handling cat litter to reduce the risk of transmission.
**Correct Answer:** B.