Biochemistry All of the following are true about Sickle cell disease, Except: A Single nucleotide change results in change of Glutamine to Valine B RFLP results from a single base change C 'Sticky patch' is generated as a result of replacement of a non polar residue with a polar residue D HbS confers resistance against malaria in heterozygotes 💡 Explanation All of the following are true about Sickle cell disease, Except: ✓ Correct Answer: C. 'Sticky patch' is generated as a result of replacement of a non polar residue with a polar residue