Occlusion of Aery of Adamkiewicz leads to infarction of which of the following structures? NOT RELATED – MEDICINE
**Core Concept**
The Artery of Adamkiewicz, also known as the great anterior radiculomedullary artery, is a vital artery supplying blood to the anterior two-thirds of the spinal cord. It typically arises from the aorta or the left posterior descending artery between T9 and L1.
**Why the Correct Answer is Right**
Occlusion of the Artery of Adamkiewicz can lead to ischemia and infarction of the spinal cord, particularly affecting the anterior two-thirds of the cord. This is because the artery supplies a significant portion of the spinal cord's blood supply, and its occlusion can compromise the blood flow to this area. The anterior spinal cord is rich in gray matter, which is responsible for the transmission of motor signals and sensory information. Infarction of this area can result in severe motor and sensory deficits.
**Why Each Wrong Option is Incorrect**
* **Option A:** The posterior spinal arteries primarily supply the posterior one-third of the spinal cord, which is not directly affected by the occlusion of the Artery of Adamkiewicz.
* **Option B:** The anterior spinal artery, while supplying a portion of the spinal cord, is not the primary artery affected by the occlusion of the Artery of Adamkiewicz.
* **Option D:** The vertebral arteries primarily supply the brain and upper spinal cord, and their occlusion would not directly result in the infarction of the anterior two-thirds of the spinal cord.
**Clinical Pearl / High-Yield Fact**
The Artery of Adamkiewicz is a critical artery that supplies a significant portion of the spinal cord's blood supply. Its occlusion can lead to severe motor and sensory deficits, making it essential to recognize and manage this condition promptly.
**Correct Answer:** C.