A 45 year old male presents to OPD with a bony pain. There is no history of trauma or drug abuse. Investigations revealed ESR of 140 and Hb -6 gm/dL. Peripheral smear is shown below . What type of chromosomal abnormality is associated with a ourable prognosis in this patient?
Correct Answer: t(11,14)
Description: A patient with bony pain, anemia, high ESR and rouleaux formation on peripheral smear is associated with likely diagnosis of multiple myeloma. The chromosomal anomaly likely to be seen in this patient with prognostic significance. Molecular Prognostic factors Cytogenetic abnormality of Multiple Myeloma Favorable PROGNOSIS Unorable PROGNOSIS t(11,14) t(4,14) t (6;14) t(14,16) Loss of 13q14
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now